Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSANAP00000001973Cyclin N-terminal domain-containing protein. (237 aa)    
Predicted Functional Partners:
CDC20
Cell division cycle 20.
   
 0.976
CDK2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.963
PLK1
Serine/threonine-protein kinase PLK.
   
 0.961
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.948
CDC20B
Cell division cycle 20B.
   
 0.947
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.942
ENSANAP00000016389
Uncharacterized protein; Belongs to the cyclin family.
   
  0.940
CCNB1
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
  0.940
CCNA2
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.939
LOC105728530
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.937
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
Server load: low (34%) [HD]