Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GPATCH11G-patch domain containing 11. (285 aa)    
Predicted Functional Partners:
DBR1
Debranching RNA lariats 1.
   
 
 0.825
PRPF8
Pre-mRNA processing factor 8.
    
 
 0.815
TFIP11
Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...]
   
 
 0.790
SYF2
SYF2 pre-mRNA splicing factor.
    
   0.769
DHX15
DEAH-box helicase 15.
   
 
 0.767
LOC105730784
TPR_REGION domain-containing protein.
    
 
 0.754
XAB2
XPA binding protein 2.
    
 
 0.754
PRPF19
Pre-mRNA processing factor 19.
   
 
 0.749
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
   
 
 0.748
CDC5L
Cell division cycle 5 like.
   
   0.748
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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