Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
AKAP10A-kinase anchoring protein 10. (633 aa)    
Predicted Functional Partners:
PRKAR2B
Uncharacterized protein.
    
 0.886
PRKAR1A
Protein kinase cAMP-dependent type I regulatory subunit alpha.
    
 0.880
PRKAR1B
Protein kinase cAMP-dependent type I regulatory subunit beta.
    
 0.880
ENSANAP00000017548
Uncharacterized protein.
    
 0.869
PRKAR2A
Uncharacterized protein.
    
 0.869
ENSANAP00000012455
Uncharacterized protein.
    
 0.863
ARFGEF1
ADP ribosylation factor guanine nucleotide exchange factor 1.
    
 
 0.793
ARFGEF2
ADP ribosylation factor guanine nucleotide exchange factor 2.
    
 
 0.789
AKAP8
A-kinase anchoring protein 8; Belongs to the AKAP95 family.
      
 0.705
HAX1
HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.
    
   0.660
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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