INSL3 protein (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

INSL3

IlGF domain-containing protein. (131 aa)

Predicted Functional Partners:

RXFP2

0.996

RXFP1

0.985

LOC105718736

0.982

RLN3

0.947

INSL5

0.932

AMH

0.793

STAR

0.757

FSHR

0.725

JAK3

0.716

RNF123

0.698

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMH	FSHR	ENSANAP00000027844	ENSANAP00000000994	Anti-Mullerian hormone.	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.	0.807
AMH	INSL3	ENSANAP00000027844	ENSANAP00000002016	Anti-Mullerian hormone.	IlGF domain-containing protein.	0.793
AMH	STAR	ENSANAP00000027844	ENSANAP00000042210	Anti-Mullerian hormone.	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	0.707
FSHR	AMH	ENSANAP00000000994	ENSANAP00000027844	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.	Anti-Mullerian hormone.	0.807
FSHR	INSL3	ENSANAP00000000994	ENSANAP00000002016	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.	IlGF domain-containing protein.	0.725
FSHR	RLN3	ENSANAP00000000994	ENSANAP00000021097	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.	Relaxin 3.	0.488
FSHR	STAR	ENSANAP00000000994	ENSANAP00000042210	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	0.527
INSL3	AMH	ENSANAP00000002016	ENSANAP00000027844	IlGF domain-containing protein.	Anti-Mullerian hormone.	0.793
INSL3	FSHR	ENSANAP00000002016	ENSANAP00000000994	IlGF domain-containing protein.	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.	0.725
INSL3	INSL5	ENSANAP00000002016	ENSANAP00000042096	IlGF domain-containing protein.	Insulin like 5.	0.932
INSL3	JAK3	ENSANAP00000002016	ENSANAP00000001288	IlGF domain-containing protein.	Tyrosine-protein kinase.	0.716
INSL3	LOC105718736	ENSANAP00000002016	ENSANAP00000011416	IlGF domain-containing protein.	IlGF domain-containing protein.	0.982
INSL3	RLN3	ENSANAP00000002016	ENSANAP00000021097	IlGF domain-containing protein.	Relaxin 3.	0.947
INSL3	RNF123	ENSANAP00000002016	ENSANAP00000031270	IlGF domain-containing protein.	Ring finger protein 123.	0.698
INSL3	RXFP1	ENSANAP00000002016	ENSANAP00000000275	IlGF domain-containing protein.	Relaxin family peptide receptor 1.	0.985
INSL3	RXFP2	ENSANAP00000002016	ENSANAP00000033307	IlGF domain-containing protein.	Relaxin family peptide receptor 2.	0.996
INSL3	STAR	ENSANAP00000002016	ENSANAP00000042210	IlGF domain-containing protein.	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	0.757
INSL5	INSL3	ENSANAP00000042096	ENSANAP00000002016	Insulin like 5.	IlGF domain-containing protein.	0.932
INSL5	LOC105718736	ENSANAP00000042096	ENSANAP00000011416	Insulin like 5.	IlGF domain-containing protein.	0.950
INSL5	RLN3	ENSANAP00000042096	ENSANAP00000021097	Insulin like 5.	Relaxin 3.	0.993