Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HERC4HECT and RLD domain containing E3 ubiquitin protein ligase 4. (1057 aa)    
Predicted Functional Partners:
ISG15
ISG15 ubiquitin like modifier.
   
 0.758
UBE2L6
Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.691
PDP1
Pyruvate dehyrogenase phosphatase catalytic subunit 1.
    
  0.679
LOC105728613
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.619
SEC24C
Uncharacterized protein.
    
   0.615
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.604
PIGY
Phosphatidylinositol glycan anchor biosynthesis class Y.
      
 0.599
PSMD4
Proteasome 26S subunit, non-ATPase 4.
    
 
 0.565
IPO11
Importin 11.
      
 0.545
MYPN
Myopalladin.
      
 0.540
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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