STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HES1Hes family bHLH transcription factor 1. (280 aa)    
Predicted Functional Partners:
FANCL
FA complementation group L.
    
 0.980
FANCG
FA complementation group G.
    
 0.979
FANCA
FA complementation group A.
    
 0.968
FANCE
FA complementation group E.
    
  0.967
FANCC
Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
    
  0.967
FANCD2
FA complementation group D2.
     
 0.906
UBE2T
Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.861
HES6
Hes family bHLH transcription factor 6.
    
0.813
NEUROG1
Neurogenin 1.
    
 0.811
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.803
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.