STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105712010Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)    
Predicted Functional Partners:
GNB3
G protein subunit beta 3.
    
 0.973
GNB2
G protein subunit beta 2.
    
 0.954
GNB4
G protein subunit beta 4.
    
 0.936
GNB1
G protein subunit beta 1.
    
 0.936
CACNA1B
Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.
     
 0.894
ADCYAP1R1
ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.
    
  0.888
MTNR1B
Melatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family.
    
  0.880
CXCR4
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
    
  0.880
LOC105728134
G_PROTEIN_RECEP_F1_2 domain-containing protein.
    
  0.880
DRD2
Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.
    
  0.880
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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