Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSANAP00000003293Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (419 aa)    
Predicted Functional Partners:
CDC20
Cell division cycle 20.
   
 0.989
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.981
CDC20B
Cell division cycle 20B.
   
 0.976
CDK2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.976
ORC1
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
 0.973
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.972
BUB1B
BUB1 N-terminal domain-containing protein.
   
 0.964
CDK3
Cyclin dependent kinase 3; Belongs to the protein kinase superfamily.
   
 0.964
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.962
ENSANAP00000033472
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.962
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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