GFI1 protein (Aotus nancymaae) - STRING interaction network

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gene neighborhood

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Score

GFI1

Growth factor independent 1 transcriptional repressor. (422 aa)

Predicted Functional Partners:

KDM1A

0.632

AK9

0.627

DDIT3

0.596

CEBPA

0.594

CEBPE

0.594

HDAC1

0.589

GATA1

0.583

UNC45B

0.571

GNA12

0.550

GATA2

0.547

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK9	GFI1	ENSANAP00000021959	ENSANAP00000003445	Adenylate kinase 9.	Growth factor independent 1 transcriptional repressor.	0.627
CEBPA	DDIT3	ENSANAP00000003354	ENSANAP00000021598	CCAAT enhancer binding protein alpha.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.648
CEBPA	GATA2	ENSANAP00000003354	ENSANAP00000021781	CCAAT enhancer binding protein alpha.	GATA binding protein 2.	0.407
CEBPA	GFI1	ENSANAP00000003354	ENSANAP00000003445	CCAAT enhancer binding protein alpha.	Growth factor independent 1 transcriptional repressor.	0.594
CEBPA	HDAC1	ENSANAP00000003354	ENSANAP00000009897	CCAAT enhancer binding protein alpha.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.406
CEBPE	DDIT3	ENSANAP00000025385	ENSANAP00000021598	CCAAT/enhancer-binding protein.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.562
CEBPE	GATA2	ENSANAP00000025385	ENSANAP00000021781	CCAAT/enhancer-binding protein.	GATA binding protein 2.	0.407
CEBPE	GFI1	ENSANAP00000025385	ENSANAP00000003445	CCAAT/enhancer-binding protein.	Growth factor independent 1 transcriptional repressor.	0.594
CEBPE	HDAC1	ENSANAP00000025385	ENSANAP00000009897	CCAAT/enhancer-binding protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.406
DDIT3	CEBPA	ENSANAP00000021598	ENSANAP00000003354	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	CCAAT enhancer binding protein alpha.	0.648
DDIT3	CEBPE	ENSANAP00000021598	ENSANAP00000025385	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	CCAAT/enhancer-binding protein.	0.562
DDIT3	GFI1	ENSANAP00000021598	ENSANAP00000003445	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Growth factor independent 1 transcriptional repressor.	0.596
GATA1	GATA2	ENSANAP00000028609	ENSANAP00000021781	GATA binding protein 1.	GATA binding protein 2.	0.647
GATA1	GFI1	ENSANAP00000028609	ENSANAP00000003445	GATA binding protein 1.	Growth factor independent 1 transcriptional repressor.	0.583
GATA1	HDAC1	ENSANAP00000028609	ENSANAP00000009897	GATA binding protein 1.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.508
GATA2	CEBPA	ENSANAP00000021781	ENSANAP00000003354	GATA binding protein 2.	CCAAT enhancer binding protein alpha.	0.407
GATA2	CEBPE	ENSANAP00000021781	ENSANAP00000025385	GATA binding protein 2.	CCAAT/enhancer-binding protein.	0.407
GATA2	GATA1	ENSANAP00000021781	ENSANAP00000028609	GATA binding protein 2.	GATA binding protein 1.	0.647
GATA2	GFI1	ENSANAP00000021781	ENSANAP00000003445	GATA binding protein 2.	Growth factor independent 1 transcriptional repressor.	0.547
GATA2	HDAC1	ENSANAP00000021781	ENSANAP00000009897	GATA binding protein 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.442