STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEF8Differentially expressed in FDCP 8 homolog. (512 aa)    
Predicted Functional Partners:
UVRAG
UV radiation resistance associated.
    
 0.706
PRSS36
Polyserase-2; Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1. Belongs to the peptidase S1 family.
      
 0.536
MTHFSD
Methenyltetrahydrofolate synthetase domain containing.
      
 0.523
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1.
      
 0.493
TREML2
Triggering receptor expressed on myeloid cells like 2.
      
 0.485
ZNF276
Zinc finger protein 276.
      
 0.485
INPP5D
Inositol polyphosphate-5-phosphatase D.
      
 0.468
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 
 0.452
BECN1
Beclin 1.
    
 
 0.434
ABI3
ABI family member 3.
      
 0.431
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.