TSG101 protein (Aotus nancymaae) - STRING interaction network

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[Homology]

Score

TSG101

Tumor susceptibility 101. (390 aa)

Predicted Functional Partners:

VPS28

0.999

VPS37B

0.997

HGS

0.991

MVB12B

0.987

MVB12A

0.984

VPS36

0.977

VPS37C

0.971

VPS37A

0.967

ENSANAP00000027878

0.967

STAM

0.950

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSANAP00000027878	HGS	ENSANAP00000027878	ENSANAP00000006705	VPS37 C-terminal domain-containing protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.729
ENSANAP00000027878	MVB12A	ENSANAP00000027878	ENSANAP00000033783	VPS37 C-terminal domain-containing protein.	Multivesicular body subunit 12A.	0.930
ENSANAP00000027878	MVB12B	ENSANAP00000027878	ENSANAP00000006803	VPS37 C-terminal domain-containing protein.	Multivesicular body subunit 12B.	0.952
ENSANAP00000027878	STAM	ENSANAP00000027878	ENSANAP00000019442	VPS37 C-terminal domain-containing protein.	Signal transducing adaptor molecule.	0.716
ENSANAP00000027878	TSG101	ENSANAP00000027878	ENSANAP00000003603	VPS37 C-terminal domain-containing protein.	Tumor susceptibility 101.	0.967
ENSANAP00000027878	VPS28	ENSANAP00000027878	ENSANAP00000007521	VPS37 C-terminal domain-containing protein.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.971
ENSANAP00000027878	VPS36	ENSANAP00000027878	ENSANAP00000010670	VPS37 C-terminal domain-containing protein.	Vacuolar protein sorting 36 homolog.	0.812
ENSANAP00000027878	VPS37B	ENSANAP00000027878	ENSANAP00000030559	VPS37 C-terminal domain-containing protein.	VPS37B subunit of ESCRT-I.	0.789
ENSANAP00000027878	VPS37C	ENSANAP00000027878	ENSANAP00000023535	VPS37 C-terminal domain-containing protein.	VPS37C subunit of ESCRT-I.	0.902
HGS	ENSANAP00000027878	ENSANAP00000006705	ENSANAP00000027878	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	VPS37 C-terminal domain-containing protein.	0.729
HGS	MVB12A	ENSANAP00000006705	ENSANAP00000033783	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Multivesicular body subunit 12A.	0.757
HGS	MVB12B	ENSANAP00000006705	ENSANAP00000006803	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Multivesicular body subunit 12B.	0.820
HGS	STAM	ENSANAP00000006705	ENSANAP00000019442	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Signal transducing adaptor molecule.	0.997
HGS	TSG101	ENSANAP00000006705	ENSANAP00000003603	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Tumor susceptibility 101.	0.991
HGS	VPS28	ENSANAP00000006705	ENSANAP00000007521	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.900
HGS	VPS36	ENSANAP00000006705	ENSANAP00000010670	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Vacuolar protein sorting 36 homolog.	0.894
HGS	VPS37A	ENSANAP00000006705	ENSANAP00000025998	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	VPS37A subunit of ESCRT-I.	0.729
HGS	VPS37B	ENSANAP00000006705	ENSANAP00000030559	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	VPS37B subunit of ESCRT-I.	0.866
HGS	VPS37C	ENSANAP00000006705	ENSANAP00000023535	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	VPS37C subunit of ESCRT-I.	0.766
MVB12A	ENSANAP00000027878	ENSANAP00000033783	ENSANAP00000027878	Multivesicular body subunit 12A.	VPS37 C-terminal domain-containing protein.	0.930