OGDH protein (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

OGDH

Oxoglutarate dehydrogenase. (1034 aa)

Predicted Functional Partners:

DLST

0.998

DLD

0.991

SUCLG1

0.986

DBT

0.979

SDHA

0.970

PDHX

0.969

LOC105723049

0.969

DLAT

0.969

IDH2

0.948

ACLY

0.943

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLY	DBT	ENSANAP00000037548	ENSANAP00000018883	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.860
ACLY	DLAT	ENSANAP00000037548	ENSANAP00000016785	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.977
ACLY	DLD	ENSANAP00000037548	ENSANAP00000004604	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Dihydrolipoyl dehydrogenase.	0.731
ACLY	DLST	ENSANAP00000037548	ENSANAP00000036952	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Dihydrolipoamide S-succinyltransferase.	0.900
ACLY	IDH2	ENSANAP00000037548	ENSANAP00000001267	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.847
ACLY	LOC105723049	ENSANAP00000037548	ENSANAP00000003564	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.892
ACLY	OGDH	ENSANAP00000037548	ENSANAP00000003786	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Oxoglutarate dehydrogenase.	0.943
ACLY	PDHX	ENSANAP00000037548	ENSANAP00000001919	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.892
ACLY	SDHA	ENSANAP00000037548	ENSANAP00000015831	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.979
ACLY	SUCLG1	ENSANAP00000037548	ENSANAP00000004383	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Succinate-CoA ligase alpha subunit.	0.994
DBT	ACLY	ENSANAP00000018883	ENSANAP00000037548	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	0.860
DBT	DLAT	ENSANAP00000018883	ENSANAP00000016785	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.658
DBT	DLD	ENSANAP00000018883	ENSANAP00000004604	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Dihydrolipoyl dehydrogenase.	0.998
DBT	DLST	ENSANAP00000018883	ENSANAP00000036952	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Dihydrolipoamide S-succinyltransferase.	0.824
DBT	IDH2	ENSANAP00000018883	ENSANAP00000001267	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.724
DBT	LOC105723049	ENSANAP00000018883	ENSANAP00000003564	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.662
DBT	OGDH	ENSANAP00000018883	ENSANAP00000003786	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Oxoglutarate dehydrogenase.	0.979
DBT	PDHX	ENSANAP00000018883	ENSANAP00000001919	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.670
DBT	SDHA	ENSANAP00000018883	ENSANAP00000015831	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.856
DBT	SUCLG1	ENSANAP00000018883	ENSANAP00000004383	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Succinate-CoA ligase alpha subunit.	0.974