| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APP | BCHE | ENSANAP00000006013 | ENSANAP00000003890 | Amyloid beta precursor protein. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.609 |
| APP | HCRT | ENSANAP00000006013 | ENSANAP00000036330 | Amyloid beta precursor protein. | Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. | 0.404 |
| BCHE | APP | ENSANAP00000003890 | ENSANAP00000006013 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Amyloid beta precursor protein. | 0.609 |
| BCHE | COCH | ENSANAP00000003890 | ENSANAP00000024016 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Cochlin. | 0.585 |
| BCHE | COLQ | ENSANAP00000003890 | ENSANAP00000020990 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Collagen like tail subunit of asymmetric acetylcholinesterase. | 0.582 |
| BCHE | CYB5R4 | ENSANAP00000003890 | ENSANAP00000005508 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Cytochrome b5 reductase 4. | 0.563 |
| BCHE | ENSANAP00000035404 | ENSANAP00000003890 | ENSANAP00000035404 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | 0.563 |
| BCHE | GHRL | ENSANAP00000003890 | ENSANAP00000024588 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Ghrelin and obestatin prepropeptide. | 0.637 |
| BCHE | GPCPD1 | ENSANAP00000003890 | ENSANAP00000033301 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Glycerophosphocholine phosphodiesterase 1. | 0.663 |
| BCHE | GUSB | ENSANAP00000003890 | ENSANAP00000041567 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | 0.545 |
| BCHE | HCRT | ENSANAP00000003890 | ENSANAP00000036330 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. | 0.571 |
| BCHE | XPR1 | ENSANAP00000003890 | ENSANAP00000035469 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Xenotropic and polytropic retrovirus receptor 1. | 0.657 |
| COCH | BCHE | ENSANAP00000024016 | ENSANAP00000003890 | Cochlin. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.585 |
| COLQ | BCHE | ENSANAP00000020990 | ENSANAP00000003890 | Collagen like tail subunit of asymmetric acetylcholinesterase. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.582 |
| CYB5R4 | BCHE | ENSANAP00000005508 | ENSANAP00000003890 | Cytochrome b5 reductase 4. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.563 |
| CYB5R4 | ENSANAP00000035404 | ENSANAP00000005508 | ENSANAP00000035404 | Cytochrome b5 reductase 4. | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | 0.980 |
| ENSANAP00000035404 | BCHE | ENSANAP00000035404 | ENSANAP00000003890 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.563 |
| ENSANAP00000035404 | CYB5R4 | ENSANAP00000035404 | ENSANAP00000005508 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Cytochrome b5 reductase 4. | 0.980 |
| GHRL | BCHE | ENSANAP00000024588 | ENSANAP00000003890 | Ghrelin and obestatin prepropeptide. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.637 |
| GHRL | HCRT | ENSANAP00000024588 | ENSANAP00000036330 | Ghrelin and obestatin prepropeptide. | Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. | 0.724 |