STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE4CPDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (684 aa)    
Predicted Functional Partners:
ADK
Adenosine kinase.
     
 0.897
DCK
Deoxycytidine kinase.
     
 0.878
PDE4B
Phosphodiesterase.
  
 
 
0.878
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
     
 0.876
APRT
Pribosyltran domain-containing protein.
     
 0.875
AK9
Adenylate kinase 9.
     
 0.873
AK3
GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
     
 0.872
PDE4D
Phosphodiesterase.
  
  
 
0.871
ADCY5
Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
    
 0.857
ADCY9
Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.809
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.