STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IDUAIduronidase alpha-L-. (651 aa)    
Predicted Functional Partners:
SGSH
N-sulfoglucosamine sulfohydrolase.
   
 
 0.918
ARSB
Arylsulfatase B.
   
 
 0.909
SPAM1
Hyaluronidase.
    
 0.882
HYAL4
Hyaluronidase.
    
 0.877
HYAL3
Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Belongs to the glycosyl hydrolase 56 family.
    
 0.875
IDS
Sulfatase domain-containing protein.
     
 0.863
HYAL1
Hyaluronidase.
    
 0.788
HYAL2
Hyaluronidase.
    
 0.776
ARSK
Arylsulfatase family member K.
     
 0.762
ARSJ
Arylsulfatase family member J.
   
 
 0.692
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.