PTPRC protein (Aotus nancymaae) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

PTPRC

Uncharacterized protein. (1299 aa)

Predicted Functional Partners:

LCK

0.982

HCK

0.952

FYN

0.938

LYN

0.937

CD22

0.921

LCP2

0.898

SEMA4D

0.890

ITGAL

0.852

CD53

0.835

IKZF1

0.833

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD22	ITGAL	ENSANAP00000025066	ENSANAP00000031593	CD22 molecule.	Integrin subunit alpha L; Belongs to the integrin alpha chain family.	0.428
CD22	LYN	ENSANAP00000025066	ENSANAP00000006027	CD22 molecule.	LYN proto-oncogene, Src family tyrosine kinase.	0.813
CD22	PTPRC	ENSANAP00000025066	ENSANAP00000004867	CD22 molecule.	Uncharacterized protein.	0.921
CD53	LCP2	ENSANAP00000031713	ENSANAP00000027507	Tetraspanin.	Lymphocyte cytosolic protein 2.	0.758
CD53	PTPRC	ENSANAP00000031713	ENSANAP00000004867	Tetraspanin.	Uncharacterized protein.	0.835
FYN	HCK	ENSANAP00000042149	ENSANAP00000039550	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.786
FYN	LCK	ENSANAP00000042149	ENSANAP00000034512	Tyrosine-protein kinase.	Tyrosine-protein kinase Lck; Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T- cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen- bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein [...]	0.911
FYN	LCP2	ENSANAP00000042149	ENSANAP00000027507	Tyrosine-protein kinase.	Lymphocyte cytosolic protein 2.	0.774
FYN	LYN	ENSANAP00000042149	ENSANAP00000006027	Tyrosine-protein kinase.	LYN proto-oncogene, Src family tyrosine kinase.	0.962
FYN	PTPRC	ENSANAP00000042149	ENSANAP00000004867	Tyrosine-protein kinase.	Uncharacterized protein.	0.938
HCK	FYN	ENSANAP00000039550	ENSANAP00000042149	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.786
HCK	LCK	ENSANAP00000039550	ENSANAP00000034512	Tyrosine-protein kinase.	Tyrosine-protein kinase Lck; Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T- cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen- bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein [...]	0.448
HCK	LCP2	ENSANAP00000039550	ENSANAP00000027507	Tyrosine-protein kinase.	Lymphocyte cytosolic protein 2.	0.766
HCK	LYN	ENSANAP00000039550	ENSANAP00000006027	Tyrosine-protein kinase.	LYN proto-oncogene, Src family tyrosine kinase.	0.936
HCK	PTPRC	ENSANAP00000039550	ENSANAP00000004867	Tyrosine-protein kinase.	Uncharacterized protein.	0.952
IKZF1	LCP2	ENSANAP00000006534	ENSANAP00000027507	IKAROS family zinc finger 1.	Lymphocyte cytosolic protein 2.	0.424
IKZF1	PTPRC	ENSANAP00000006534	ENSANAP00000004867	IKAROS family zinc finger 1.	Uncharacterized protein.	0.833
ITGAL	CD22	ENSANAP00000031593	ENSANAP00000025066	Integrin subunit alpha L; Belongs to the integrin alpha chain family.	CD22 molecule.	0.428
ITGAL	LCK	ENSANAP00000031593	ENSANAP00000034512	Integrin subunit alpha L; Belongs to the integrin alpha chain family.	Tyrosine-protein kinase Lck; Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T- cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen- bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein [...]	0.439
ITGAL	PTPRC	ENSANAP00000031593	ENSANAP00000004867	Integrin subunit alpha L; Belongs to the integrin alpha chain family.	Uncharacterized protein.	0.852