Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIX4SIX homeobox 4. (773 aa)    
Predicted Functional Partners:
EYA2
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 0.844
EYA1
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 0.794
EYA3
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 0.778
EYA4
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 0.731
PAX8
Paired box 8.
     
 0.607
PAX2
Paired box 2.
     
 0.530
PAX5
Paired box 5.
     
 0.530
SMPD1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
      
 0.515
EMX2
Empty spiracles homeobox 2.
  
   
 0.497
BHLHE40
Basic helix-loop-helix family member e40.
      
 0.464
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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