STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB2Growth factor receptor bound protein 2. (217 aa)    
Predicted Functional Partners:
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.999
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
   
 0.998
SHC1
SHC adaptor protein 1.
   
 0.998
GAB1
GRB2 associated binding protein 1.
    
 0.996
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.996
EGFR
Epidermal growth factor receptor.
    
 0.996
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
0.995
LAT
Linker for activation of T cells.
    
 0.993
FRS2
Fibroblast growth factor receptor substrate 2.
    
 0.993
CBL
Cbl proto-oncogene.
    
 0.993
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.