| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BGLAP | IBSP | ENSANAP00000034481 | ENSANAP00000041081 | Osteocalcin; Binds strongly to apatite and calcium. | Integrin binding sialoprotein. | 0.743 |
| BGLAP | RUNX1 | ENSANAP00000034481 | ENSANAP00000024288 | Osteocalcin; Binds strongly to apatite and calcium. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.769 |
| BGLAP | RUNX3 | ENSANAP00000034481 | ENSANAP00000024592 | Osteocalcin; Binds strongly to apatite and calcium. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.769 |
| BGLAP | SP7 | ENSANAP00000034481 | ENSANAP00000005367 | Osteocalcin; Binds strongly to apatite and calcium. | Sp7 transcription factor. | 0.503 |
| BGLAP | SPP1 | ENSANAP00000034481 | ENSANAP00000034456 | Osteocalcin; Binds strongly to apatite and calcium. | Secreted phosphoprotein 1. | 0.720 |
| BGLAP | TNFSF11 | ENSANAP00000034481 | ENSANAP00000013648 | Osteocalcin; Binds strongly to apatite and calcium. | Tumor necrosis factor ligand superfamily member. | 0.657 |
| IBSP | BGLAP | ENSANAP00000041081 | ENSANAP00000034481 | Integrin binding sialoprotein. | Osteocalcin; Binds strongly to apatite and calcium. | 0.743 |
| IBSP | RUNX1 | ENSANAP00000041081 | ENSANAP00000024288 | Integrin binding sialoprotein. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.454 |
| IBSP | SP7 | ENSANAP00000041081 | ENSANAP00000005367 | Integrin binding sialoprotein. | Sp7 transcription factor. | 0.598 |
| IBSP | SPP1 | ENSANAP00000041081 | ENSANAP00000034456 | Integrin binding sialoprotein. | Secreted phosphoprotein 1. | 0.724 |
| IBSP | TNFSF11 | ENSANAP00000041081 | ENSANAP00000013648 | Integrin binding sialoprotein. | Tumor necrosis factor ligand superfamily member. | 0.531 |
| NCOA1 | SP7 | ENSANAP00000009590 | ENSANAP00000005367 | Nuclear receptor coactivator. | Sp7 transcription factor. | 0.534 |
| PLOD2 | SP7 | ENSANAP00000025565 | ENSANAP00000005367 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. | Sp7 transcription factor. | 0.607 |
| RUNX1 | BGLAP | ENSANAP00000024288 | ENSANAP00000034481 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Osteocalcin; Binds strongly to apatite and calcium. | 0.769 |
| RUNX1 | IBSP | ENSANAP00000024288 | ENSANAP00000041081 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Integrin binding sialoprotein. | 0.454 |
| RUNX1 | RUNX3 | ENSANAP00000024288 | ENSANAP00000024592 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.819 |
| RUNX1 | SP7 | ENSANAP00000024288 | ENSANAP00000005367 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Sp7 transcription factor. | 0.500 |
| RUNX1 | SPP1 | ENSANAP00000024288 | ENSANAP00000034456 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Secreted phosphoprotein 1. | 0.666 |
| RUNX1 | TNFSF11 | ENSANAP00000024288 | ENSANAP00000013648 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Tumor necrosis factor ligand superfamily member. | 0.477 |
| RUNX3 | BGLAP | ENSANAP00000024592 | ENSANAP00000034481 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Osteocalcin; Binds strongly to apatite and calcium. | 0.769 |