| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADK | AK4 | ENSANAP00000036011 | ENSANAP00000000491 | Adenosine kinase. | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | 0.932 |
| ADK | AK6 | ENSANAP00000036011 | ENSANAP00000005485 | Adenosine kinase. | Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. | 0.881 |
| ADK | AK7 | ENSANAP00000036011 | ENSANAP00000011060 | Adenosine kinase. | Adenylate kinase 7. | 0.932 |
| ADK | AK8 | ENSANAP00000036011 | ENSANAP00000015165 | Adenosine kinase. | Adenylate kinase 8; Belongs to the adenylate kinase family. | 0.961 |
| ADK | AK9 | ENSANAP00000036011 | ENSANAP00000021959 | Adenosine kinase. | Adenylate kinase 9. | 0.954 |
| ADK | APRT | ENSANAP00000036011 | ENSANAP00000039604 | Adenosine kinase. | Pribosyltran domain-containing protein. | 0.978 |
| ADK | ENPP1 | ENSANAP00000036011 | ENSANAP00000008000 | Adenosine kinase. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.917 |
| ADK | ENPP3 | ENSANAP00000036011 | ENSANAP00000024605 | Adenosine kinase. | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | 0.887 |
| ADK | LOC105733134 | ENSANAP00000036011 | ENSANAP00000021594 | Adenosine kinase. | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. | 0.965 |
| AK4 | ADK | ENSANAP00000000491 | ENSANAP00000036011 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Adenosine kinase. | 0.932 |
| AK4 | AK6 | ENSANAP00000000491 | ENSANAP00000005485 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. | 0.873 |
| AK4 | AK7 | ENSANAP00000000491 | ENSANAP00000011060 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Adenylate kinase 7. | 0.910 |
| AK4 | AK8 | ENSANAP00000000491 | ENSANAP00000015165 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Adenylate kinase 8; Belongs to the adenylate kinase family. | 0.870 |
| AK4 | AK9 | ENSANAP00000000491 | ENSANAP00000021959 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Adenylate kinase 9. | 0.898 |
| AK4 | APRT | ENSANAP00000000491 | ENSANAP00000039604 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Pribosyltran domain-containing protein. | 0.929 |
| AK4 | ENPP1 | ENSANAP00000000491 | ENSANAP00000008000 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.904 |
| AK4 | ENPP3 | ENSANAP00000000491 | ENSANAP00000024605 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | 0.869 |
| AK4 | LOC105733134 | ENSANAP00000000491 | ENSANAP00000021594 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. | 0.886 |
| AK4 | RRM1 | ENSANAP00000000491 | ENSANAP00000013526 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.914 |
| AK6 | ADK | ENSANAP00000005485 | ENSANAP00000036011 | Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. | Adenosine kinase. | 0.881 |