STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105709072HATPase_c domain-containing protein. (329 aa)    
Predicted Functional Partners:
CDC37
Cell division cycle 37.
    
 0.970
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.969
AR
Androgen receptor.
    
 0.967
SUGT1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
    
 0.964
PTGES3
Prostaglandin E synthase 3.
   
 0.956
AHR
Uncharacterized protein.
    
 0.935
FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) (By similarity). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded. Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1 (By similarity).
   
 0.934
LOC105707901
Uncharacterized protein.
   
 0.926
STUB1
STIP1 homology and U-box containing protein 1.
    
 0.926
STIP1
Stress induced phosphoprotein 1.
   
 0.926
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.