STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSANAP00000006063SH2 domain-containing protein. (230 aa)    
Predicted Functional Partners:
EGFR
Epidermal growth factor receptor.
    
 0.989
JAK2
Tyrosine-protein kinase.
   
 0.978
IRF9
Interferon regulatory factor 9.
   
 0.978
JAK1
Tyrosine-protein kinase.
   
 0.977
TYK2
Tyrosine-protein kinase.
   
 0.968
JAK3
Tyrosine-protein kinase.
   
 0.965
IL2RA
Interleukin 2 receptor subunit alpha.
    
 0.965
ERBB4
Receptor protein-tyrosine kinase.
    
 0.964
CISH
Cytokine inducible SH2 containing protein.
    
 0.942
STAT5B
Signal transducer and activator of transcription.
  
0.942
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.