node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATAD2 | ENSANAP00000031031 | ENSANAP00000006168 | ENSANAP00000031031 | ATPase family AAA domain containing 2. | Uncharacterized protein. | 0.814 |
ATAD2 | ESR1 | ENSANAP00000006168 | ENSANAP00000032641 | ATPase family AAA domain containing 2. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.865 |
ATAD2 | GPD2 | ENSANAP00000006168 | ENSANAP00000022721 | ATPase family AAA domain containing 2. | Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.884 |
ATAD2 | MCM4 | ENSANAP00000006168 | ENSANAP00000017109 | ATPase family AAA domain containing 2. | DNA helicase; Belongs to the MCM family. | 0.836 |
ATAD2 | PSMD1 | ENSANAP00000006168 | ENSANAP00000003086 | ATPase family AAA domain containing 2. | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | 0.823 |
ATAD2 | PSMD11 | ENSANAP00000006168 | ENSANAP00000007452 | ATPase family AAA domain containing 2. | Proteasome 26S subunit, non-ATPase 11. | 0.845 |
ATAD2 | PSMD13 | ENSANAP00000006168 | ENSANAP00000003944 | ATPase family AAA domain containing 2. | Proteasome 26S subunit, non-ATPase 13. | 0.842 |
ATAD2 | PSMD2 | ENSANAP00000006168 | ENSANAP00000002394 | ATPase family AAA domain containing 2. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.845 |
ATAD2 | PSMD4 | ENSANAP00000006168 | ENSANAP00000011866 | ATPase family AAA domain containing 2. | Proteasome 26S subunit, non-ATPase 4. | 0.843 |
ATAD2 | PSMD6 | ENSANAP00000006168 | ENSANAP00000036111 | ATPase family AAA domain containing 2. | Proteasome 26S subunit, non-ATPase 6. | 0.866 |
ENSANAP00000031031 | ATAD2 | ENSANAP00000031031 | ENSANAP00000006168 | Uncharacterized protein. | ATPase family AAA domain containing 2. | 0.814 |
ENSANAP00000031031 | MCM4 | ENSANAP00000031031 | ENSANAP00000017109 | Uncharacterized protein. | DNA helicase; Belongs to the MCM family. | 0.713 |
ESR1 | ATAD2 | ENSANAP00000032641 | ENSANAP00000006168 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | ATPase family AAA domain containing 2. | 0.865 |
GPD2 | ATAD2 | ENSANAP00000022721 | ENSANAP00000006168 | Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | ATPase family AAA domain containing 2. | 0.884 |
MCM4 | ATAD2 | ENSANAP00000017109 | ENSANAP00000006168 | DNA helicase; Belongs to the MCM family. | ATPase family AAA domain containing 2. | 0.836 |
MCM4 | ENSANAP00000031031 | ENSANAP00000017109 | ENSANAP00000031031 | DNA helicase; Belongs to the MCM family. | Uncharacterized protein. | 0.713 |
PSMD1 | ATAD2 | ENSANAP00000003086 | ENSANAP00000006168 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | ATPase family AAA domain containing 2. | 0.823 |
PSMD1 | PSMD11 | ENSANAP00000003086 | ENSANAP00000007452 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | Proteasome 26S subunit, non-ATPase 11. | 0.999 |
PSMD1 | PSMD13 | ENSANAP00000003086 | ENSANAP00000003944 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | Proteasome 26S subunit, non-ATPase 13. | 0.998 |
PSMD1 | PSMD2 | ENSANAP00000003086 | ENSANAP00000002394 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.999 |