Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (437 aa)    
Predicted Functional Partners:
CRHR1
Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family.
  
 
0.969
POMC
Proopiomelanocortin.
   
 0.966
ADCYAP1
Adenylate cyclase activating polypeptide 1.
    
 0.951
VIP
Vasoactive intestinal peptide.
   
 0.933
GCG
Glucagon.
   
 0.927
LOC105727565
GNAS complex locus.
    
 0.922
CGA
Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
   
 
 0.907
NPPA
Natriuretic peptide A.
     
 0.900
LOC105727567
Uncharacterized protein.
     
  0.900
GNB2
G protein subunit beta 2.
    
  0.887
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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