HDAC6 protein (Aotus nancymaae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

HDAC6

Histone deacetylase 6. (1226 aa)

Predicted Functional Partners:

TARDBP

0.890

ARID4A

0.888

ARID4B

0.888

HSP90AA1

0.869

UBA52

0.852

LOC105732229

0.827

LOC105713378

0.827

PRKN

0.823

LOC105719658

0.797

RPS27A

0.797

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID4A	ARID4B	ENSANAP00000040454	ENSANAP00000041612	AT-rich interaction domain 4A.	AT-rich interaction domain 4B.	0.569
ARID4A	HDAC6	ENSANAP00000040454	ENSANAP00000006328	AT-rich interaction domain 4A.	Histone deacetylase 6.	0.888
ARID4B	ARID4A	ENSANAP00000041612	ENSANAP00000040454	AT-rich interaction domain 4B.	AT-rich interaction domain 4A.	0.569
ARID4B	HDAC6	ENSANAP00000041612	ENSANAP00000006328	AT-rich interaction domain 4B.	Histone deacetylase 6.	0.888
HDAC6	ARID4A	ENSANAP00000006328	ENSANAP00000040454	Histone deacetylase 6.	AT-rich interaction domain 4A.	0.888
HDAC6	ARID4B	ENSANAP00000006328	ENSANAP00000041612	Histone deacetylase 6.	AT-rich interaction domain 4B.	0.888
HDAC6	HSP90AA1	ENSANAP00000006328	ENSANAP00000039061	Histone deacetylase 6.	Heat shock protein 90 alpha family class A member 1.	0.869
HDAC6	LOC105713378	ENSANAP00000006328	ENSANAP00000026759	Histone deacetylase 6.	Ubiquitin-like domain-containing protein.	0.827
HDAC6	LOC105719658	ENSANAP00000006328	ENSANAP00000003834	Histone deacetylase 6.	Ubiquitin-like domain-containing protein.	0.797
HDAC6	LOC105732229	ENSANAP00000006328	ENSANAP00000026684	Histone deacetylase 6.	Ubiquitin-like domain-containing protein.	0.827
HDAC6	PRKN	ENSANAP00000006328	ENSANAP00000028998	Histone deacetylase 6.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.823
HDAC6	RPS27A	ENSANAP00000006328	ENSANAP00000041829	Histone deacetylase 6.	Ubiquitin-like domain-containing protein.	0.797
HDAC6	TARDBP	ENSANAP00000006328	ENSANAP00000035619	Histone deacetylase 6.	TAR DNA binding protein.	0.890
HDAC6	UBA52	ENSANAP00000006328	ENSANAP00000039916	Histone deacetylase 6.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.852
HSP90AA1	HDAC6	ENSANAP00000039061	ENSANAP00000006328	Heat shock protein 90 alpha family class A member 1.	Histone deacetylase 6.	0.869
HSP90AA1	LOC105713378	ENSANAP00000039061	ENSANAP00000026759	Heat shock protein 90 alpha family class A member 1.	Ubiquitin-like domain-containing protein.	0.488
HSP90AA1	LOC105719658	ENSANAP00000039061	ENSANAP00000003834	Heat shock protein 90 alpha family class A member 1.	Ubiquitin-like domain-containing protein.	0.426
HSP90AA1	LOC105732229	ENSANAP00000039061	ENSANAP00000026684	Heat shock protein 90 alpha family class A member 1.	Ubiquitin-like domain-containing protein.	0.488
HSP90AA1	PRKN	ENSANAP00000039061	ENSANAP00000028998	Heat shock protein 90 alpha family class A member 1.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.487
HSP90AA1	RPS27A	ENSANAP00000039061	ENSANAP00000041829	Heat shock protein 90 alpha family class A member 1.	Ubiquitin-like domain-containing protein.	0.426