TIRAP protein (Aotus nancymaae) - STRING interaction network

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Score

TIRAP

TIR domain containing adaptor protein. (221 aa)

Predicted Functional Partners:

MYD88

0.996

TLR4

0.996

TRAF6

0.994

IRAK4

0.990

IRAK1

0.985

TLR6

0.981

LOC105722888

0.962

LY96

0.950

FADD

0.923

IRAK2

0.895

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FADD	LY96	ENSANAP00000026219	ENSANAP00000000003	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Lymphocyte antigen 96.	0.582
FADD	MYD88	ENSANAP00000026219	ENSANAP00000011543	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.976
FADD	TIRAP	ENSANAP00000026219	ENSANAP00000006348	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	TIR domain containing adaptor protein.	0.923
FADD	TLR4	ENSANAP00000026219	ENSANAP00000017232	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.707
FADD	TRAF6	ENSANAP00000026219	ENSANAP00000020369	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.938
IRAK1	IRAK2	ENSANAP00000026140	ENSANAP00000028234	Interleukin 1 receptor associated kinase 1.	Interleukin 1 receptor associated kinase 2.	0.994
IRAK1	IRAK4	ENSANAP00000026140	ENSANAP00000005286	Interleukin 1 receptor associated kinase 1.	Interleukin 1 receptor associated kinase 4.	0.999
IRAK1	LOC105722888	ENSANAP00000026140	ENSANAP00000022254	Interleukin 1 receptor associated kinase 1.	TIR domain-containing protein.	0.674
IRAK1	LY96	ENSANAP00000026140	ENSANAP00000000003	Interleukin 1 receptor associated kinase 1.	Lymphocyte antigen 96.	0.717
IRAK1	MYD88	ENSANAP00000026140	ENSANAP00000011543	Interleukin 1 receptor associated kinase 1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.999
IRAK1	TIRAP	ENSANAP00000026140	ENSANAP00000006348	Interleukin 1 receptor associated kinase 1.	TIR domain containing adaptor protein.	0.985
IRAK1	TLR4	ENSANAP00000026140	ENSANAP00000017232	Interleukin 1 receptor associated kinase 1.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.808
IRAK1	TLR6	ENSANAP00000026140	ENSANAP00000028007	Interleukin 1 receptor associated kinase 1.	Toll-like receptor.	0.485
IRAK1	TRAF6	ENSANAP00000026140	ENSANAP00000020369	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
IRAK2	IRAK1	ENSANAP00000028234	ENSANAP00000026140	Interleukin 1 receptor associated kinase 2.	Interleukin 1 receptor associated kinase 1.	0.994
IRAK2	IRAK4	ENSANAP00000028234	ENSANAP00000005286	Interleukin 1 receptor associated kinase 2.	Interleukin 1 receptor associated kinase 4.	0.997
IRAK2	LOC105722888	ENSANAP00000028234	ENSANAP00000022254	Interleukin 1 receptor associated kinase 2.	TIR domain-containing protein.	0.517
IRAK2	LY96	ENSANAP00000028234	ENSANAP00000000003	Interleukin 1 receptor associated kinase 2.	Lymphocyte antigen 96.	0.702
IRAK2	MYD88	ENSANAP00000028234	ENSANAP00000011543	Interleukin 1 receptor associated kinase 2.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.993
IRAK2	TIRAP	ENSANAP00000028234	ENSANAP00000006348	Interleukin 1 receptor associated kinase 2.	TIR domain containing adaptor protein.	0.895