STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCA7ATP binding cassette subfamily A member 7. (2146 aa)    
Predicted Functional Partners:
PICALM
Phosphatidylinositol binding clathrin assembly protein.
      
 0.614
CD2AP
CD2 associated protein.
      
 0.609
CD33
CD33 molecule.
      
 0.581
EPHA1
EPH receptor A1.
      
 0.581
CLU
Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.
    
 
 0.579
TREM2
Triggering receptor expressed on myeloid cells 2.
      
 0.572
SORL1
Sortilin related receptor 1.
    
 
 0.551
NME8
NME/NM23 family member 8.
     
 0.546
BIN1
Bridging integrator 1.
      
 0.524
PSEN2
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
      
 0.524
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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