STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB7Growth factor receptor bound protein 7. (554 aa)    
Predicted Functional Partners:
ERBB2
Receptor protein-tyrosine kinase.
   
 0.961
ERBB3
Erb-b2 receptor tyrosine kinase 3.
   
 0.744
EGFR
Epidermal growth factor receptor.
   
 0.719
GRB2
Growth factor receptor bound protein 2.
    
 0.702
SHC1
SHC adaptor protein 1.
    
0.670
RND1
Rho family GTPase 1.
    
 0.664
WDR90
WD repeat domain 90.
    
  0.663
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.661
ERBB4
Receptor protein-tyrosine kinase.
   
 0.649
KIT
Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.636
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.