STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP7Caspase 7; Belongs to the peptidase C14A family. (280 aa)    
Predicted Functional Partners:
XIAP
X-linked inhibitor of apoptosis.
   
 0.996
BIRC2
Baculoviral IAP repeat containing 2.
   
 0.986
PARP1
Poly [ADP-ribose] polymerase.
    
 0.973
BIRC7
Baculoviral IAP repeat containing 7.
   
 0.973
BIRC3
Baculoviral IAP repeat containing 3.
   
 0.955
CASP9
Caspase 9; Belongs to the peptidase C14A family.
    
0.950
CASP8
Caspase 8; Belongs to the peptidase C14A family.
   
0.943
CASP10
Caspase 10; Belongs to the peptidase C14A family.
   
0.936
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.936
PARP3
Poly [ADP-ribose] polymerase.
    
 0.923
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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