LOC105704815 protein (Aotus nancymaae) - STRING interaction network

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Score

LOC105704815

DED domain-containing protein. (302 aa)

Predicted Functional Partners:

CASP8

0.767

FADD

0.727

CFLAR

0.670

CASP10

0.619

REXO4

0.574

ISG20L2

0.571

ERI1

0.464

STRN4

0.445

FBXO38

0.438

XRN1

0.406

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP10	CASP8	ENSANAP00000002346	ENSANAP00000022104	Caspase 10; Belongs to the peptidase C14A family.	Caspase 8; Belongs to the peptidase C14A family.	0.997
CASP10	CFLAR	ENSANAP00000002346	ENSANAP00000013283	Caspase 10; Belongs to the peptidase C14A family.	CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.	0.997
CASP10	FADD	ENSANAP00000002346	ENSANAP00000026219	Caspase 10; Belongs to the peptidase C14A family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.998
CASP10	LOC105704815	ENSANAP00000002346	ENSANAP00000007175	Caspase 10; Belongs to the peptidase C14A family.	DED domain-containing protein.	0.619
CASP8	CASP10	ENSANAP00000022104	ENSANAP00000002346	Caspase 8; Belongs to the peptidase C14A family.	Caspase 10; Belongs to the peptidase C14A family.	0.997
CASP8	CFLAR	ENSANAP00000022104	ENSANAP00000013283	Caspase 8; Belongs to the peptidase C14A family.	CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.	0.998
CASP8	FADD	ENSANAP00000022104	ENSANAP00000026219	Caspase 8; Belongs to the peptidase C14A family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.999
CASP8	LOC105704815	ENSANAP00000022104	ENSANAP00000007175	Caspase 8; Belongs to the peptidase C14A family.	DED domain-containing protein.	0.767
CFLAR	CASP10	ENSANAP00000013283	ENSANAP00000002346	CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.	Caspase 10; Belongs to the peptidase C14A family.	0.997
CFLAR	CASP8	ENSANAP00000013283	ENSANAP00000022104	CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.	Caspase 8; Belongs to the peptidase C14A family.	0.998
CFLAR	FADD	ENSANAP00000013283	ENSANAP00000026219	CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.997
CFLAR	LOC105704815	ENSANAP00000013283	ENSANAP00000007175	CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.	DED domain-containing protein.	0.670
ERI1	LOC105704815	ENSANAP00000011297	ENSANAP00000007175	Exoribonuclease 1.	DED domain-containing protein.	0.464
ERI1	XRN1	ENSANAP00000011297	ENSANAP00000022949	Exoribonuclease 1.	5'-3' exoribonuclease 1.	0.599
FADD	CASP10	ENSANAP00000026219	ENSANAP00000002346	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Caspase 10; Belongs to the peptidase C14A family.	0.998
FADD	CASP8	ENSANAP00000026219	ENSANAP00000022104	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Caspase 8; Belongs to the peptidase C14A family.	0.999
FADD	CFLAR	ENSANAP00000026219	ENSANAP00000013283	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.	0.997
FADD	LOC105704815	ENSANAP00000026219	ENSANAP00000007175	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	DED domain-containing protein.	0.727
FBXO38	LOC105704815	ENSANAP00000014388	ENSANAP00000007175	F-box protein 38.	DED domain-containing protein.	0.438
ISG20L2	LOC105704815	ENSANAP00000017550	ENSANAP00000007175	Interferon stimulated exonuclease gene 20 like 2.	DED domain-containing protein.	0.571