STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1073 aa)    
Predicted Functional Partners:
PLXNA1
Plexin A1.
    
0.943
SEMA6A
Semaphorin 6A; Belongs to the semaphorin family.
  
  
 
0.872
PLXNA3
Plexin A3.
    
0.856
PLXNA4
Plexin A4.
    
0.802
PLXNA2
Plexin A2.
    
0.774
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
 0.680
MST1R
Macrophage stimulating 1 receptor.
    
 0.680
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.628
TREM2
Triggering receptor expressed on myeloid cells 2.
     
 0.613
SLC25A21
Solute carrier family 25 member 21; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.609
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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