Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2364 aa)    
Predicted Functional Partners:
SPTAN1
Spectrin alpha, non-erythrocytic 1.
   
 0.998
SPTA1
Spectrin alpha, erythrocytic 1.
   
0.908
SPTBN2
Spectrin beta chain; Belongs to the spectrin family.
  
 
0.846
NF2
Neurofibromin 2.
    
 0.840
ANK3
Ankyrin 3.
   
 0.829
ANLN
Anillin actin binding protein.
    
 
 0.768
CEP63
Centrosomal protein 63.
    
   0.732
ADD2
Adducin 2.
    
 
 0.724
WDR76
WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.
    
   0.699
SNCA
Alpha-synuclein; Belongs to the synuclein family.
    
   0.699
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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