Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TYRTyrosinase. (530 aa)    
Predicted Functional Partners:
TRPM1
Transient receptor potential cation channel subfamily M member 1.
   
  
 0.984
MLANA
Melan-A.
   
  
 0.952
TAT
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
     
 0.921
TH
Tyrosine hydroxylase.
     
 0.916
DDC
Dopa decarboxylase.
     
 0.915
PRKCB
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.910
GOT2
Aspartate aminotransferase.
    
 0.909
IL4I1
Amine oxidase.
    
  0.904
TPO
Thyroid peroxidase.
     
 0.902
GOT1
Aspartate aminotransferase.
    
  0.901
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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