STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMIGD3Transmembrane and immunoglobulin domain containing 3; Belongs to the G-protein coupled receptor 1 family. (347 aa)    
Predicted Functional Partners:
ADORA1
Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
   
 
0.877
GNAI2
G protein subunit alpha i2.
    
  0.780
OPRD1
Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.
     
 0.777
KNG1
Kininogen 1.
    
  0.766
VSIG4
V-set and immunoglobulin domain containing 4.
   
    0.744
ADORA2A
Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
     
0.693
LOC105734680
Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
     
0.641
OPRM1
Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family.
     
 0.618
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.534
GNAI3
Uncharacterized protein.
    
  0.511
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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