Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (776 aa)    
Predicted Functional Partners:
GIT1
GIT ArfGAP 1.
   
 0.998
PAK1
Non-specific serine/threonine protein kinase.
    
 0.997
ARHGEF7
Rho guanine nucleotide exchange factor 7.
  
0.995
PAK3
P21 (RAC1) activated kinase 3.
    
 0.991
PAK2
Non-specific serine/threonine protein kinase.
   
 0.990
GIT2
GIT ArfGAP 2.
   
 0.983
RAC3
Rac family small GTPase 3.
   
 0.970
RAC2
Rac family small GTPase 2.
   
 0.970
PAK5
Non-specific serine/threonine protein kinase.
    
 0.961
PAK4
Non-specific serine/threonine protein kinase.
    
 0.961
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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