STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)    
Predicted Functional Partners:
NCOR1
Nuclear receptor corepressor 1.
    
 0.990
NCOR2
Nuclear receptor corepressor 2.
    
 0.987
SIN3A
SIN3 transcription regulator family member A.
   
 0.979
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.958
GPS2
G protein pathway suppressor 2.
    
 0.955
ARID4A
AT-rich interaction domain 4A.
    
 0.951
ARID4B
AT-rich interaction domain 4B.
    
 0.951
TBL1XR1
Transducin beta like 1 X-linked receptor 1.
   
 0.941
SUDS3
SDS3 homolog, SIN3A corepressor complex component.
    
 0.938
TBL1X
Transducin beta like 1 X-linked.
   
 0.933
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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