Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4074 aa)    
Predicted Functional Partners:
AP5B1
Adaptor related protein complex 5 subunit beta 1.
      
 0.622
PKD2
Polycystin 2, transient receptor potential cation channel.
      
 0.614
PKD1
Polycystin 1, transient receptor potential channel interacting.
      
 0.604
UMOD
Uromodulin.
      
 0.574
RP1L1
RP1 like 1.
      
 0.542
TMIGD1
Transmembrane and immunoglobulin domain containing 1.
      
 0.540
SACS
Sacsin molecular chaperone.
      
 0.521
TULP3
Tubby-like protein; Belongs to the TUB family.
      
 0.482
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.481
IFT88
Intraflagellar transport 88.
      
 0.471
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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