| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASS1 | CAD | ENSANAP00000023758 | ENSANAP00000009350 | Uncharacterized protein. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.939 |
| ASS1 | GFPT1 | ENSANAP00000023758 | ENSANAP00000009201 | Uncharacterized protein. | Glutamine--fructose-6-phosphate transaminase 1. | 0.426 |
| ASS1 | GFPT2 | ENSANAP00000023758 | ENSANAP00000014479 | Uncharacterized protein. | Glutamine-fructose-6-phosphate transaminase 2. | 0.426 |
| ASS1 | OTC | ENSANAP00000023758 | ENSANAP00000042329 | Uncharacterized protein. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.970 |
| ASS1 | PPAT | ENSANAP00000023758 | ENSANAP00000026828 | Uncharacterized protein. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.612 |
| CAD | ASS1 | ENSANAP00000009350 | ENSANAP00000023758 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uncharacterized protein. | 0.939 |
| CAD | DHODH | ENSANAP00000009350 | ENSANAP00000006953 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.989 |
| CAD | DPYD | ENSANAP00000009350 | ENSANAP00000038596 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.944 |
| CAD | ENSANAP00000002382 | ENSANAP00000009350 | ENSANAP00000002382 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uncharacterized protein. | 0.938 |
| CAD | ENSANAP00000010133 | ENSANAP00000009350 | ENSANAP00000010133 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uncharacterized protein. | 0.937 |
| CAD | ENSANAP00000012350 | ENSANAP00000009350 | ENSANAP00000012350 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uncharacterized protein. | 0.937 |
| CAD | GFPT1 | ENSANAP00000009350 | ENSANAP00000009201 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutamine--fructose-6-phosphate transaminase 1. | 0.937 |
| CAD | GFPT2 | ENSANAP00000009350 | ENSANAP00000014479 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutamine-fructose-6-phosphate transaminase 2. | 0.937 |
| CAD | OTC | ENSANAP00000009350 | ENSANAP00000042329 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.983 |
| CAD | PPAT | ENSANAP00000009350 | ENSANAP00000026828 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.988 |
| DHODH | CAD | ENSANAP00000006953 | ENSANAP00000009350 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.989 |
| DHODH | DPYD | ENSANAP00000006953 | ENSANAP00000038596 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.497 |
| DHODH | PPAT | ENSANAP00000006953 | ENSANAP00000026828 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.654 |
| DPYD | CAD | ENSANAP00000038596 | ENSANAP00000009350 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.944 |
| DPYD | DHODH | ENSANAP00000038596 | ENSANAP00000006953 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.497 |