STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (907 aa)    
Predicted Functional Partners:
TICAM1
Toll like receptor adaptor molecule 1.
   
 0.989
UNC93B1
Unc-93 homolog B1, TLR signaling regulator.
    
 0.973
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.972
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.965
TICAM2
Toll like receptor adaptor molecule 2.
   
 0.955
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.954
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    
 0.945
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
    
 0.936
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
    
 0.925
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.920
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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