TICAM1 protein (Aotus nancymaae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

TICAM1

Toll like receptor adaptor molecule 1. (538 aa)

Predicted Functional Partners:

TLR3

0.989

TLR4

0.987

TRAF6

0.986

IRF3

0.980

RIPK1

0.978

TRAF3

0.966

TMED2

0.943

RIPK3

0.924

TBK1

0.920

LOC105722888

0.920

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IRF3	LOC105722888	ENSANAP00000029921	ENSANAP00000022254	Interferon regulatory factor 3.	TIR domain-containing protein.	0.520
IRF3	RIPK1	ENSANAP00000029921	ENSANAP00000031154	Interferon regulatory factor 3.	Receptor interacting serine/threonine kinase 1.	0.459
IRF3	TBK1	ENSANAP00000029921	ENSANAP00000021446	Interferon regulatory factor 3.	TANK binding kinase 1.	0.996
IRF3	TICAM1	ENSANAP00000029921	ENSANAP00000009967	Interferon regulatory factor 3.	Toll like receptor adaptor molecule 1.	0.980
IRF3	TLR3	ENSANAP00000029921	ENSANAP00000009875	Interferon regulatory factor 3.	Toll like receptor 3; Belongs to the Toll-like receptor family.	0.803
IRF3	TLR4	ENSANAP00000029921	ENSANAP00000017232	Interferon regulatory factor 3.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.776
IRF3	TRAF3	ENSANAP00000029921	ENSANAP00000009518	Interferon regulatory factor 3.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.806
IRF3	TRAF6	ENSANAP00000029921	ENSANAP00000020369	Interferon regulatory factor 3.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.612
LOC105722888	IRF3	ENSANAP00000022254	ENSANAP00000029921	TIR domain-containing protein.	Interferon regulatory factor 3.	0.520
LOC105722888	TBK1	ENSANAP00000022254	ENSANAP00000021446	TIR domain-containing protein.	TANK binding kinase 1.	0.524
LOC105722888	TICAM1	ENSANAP00000022254	ENSANAP00000009967	TIR domain-containing protein.	Toll like receptor adaptor molecule 1.	0.920
LOC105722888	TLR3	ENSANAP00000022254	ENSANAP00000009875	TIR domain-containing protein.	Toll like receptor 3; Belongs to the Toll-like receptor family.	0.719
LOC105722888	TLR4	ENSANAP00000022254	ENSANAP00000017232	TIR domain-containing protein.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.934
LOC105722888	TRAF3	ENSANAP00000022254	ENSANAP00000009518	TIR domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.504
LOC105722888	TRAF6	ENSANAP00000022254	ENSANAP00000020369	TIR domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.622
RIPK1	IRF3	ENSANAP00000031154	ENSANAP00000029921	Receptor interacting serine/threonine kinase 1.	Interferon regulatory factor 3.	0.459
RIPK1	RIPK3	ENSANAP00000031154	ENSANAP00000031683	Receptor interacting serine/threonine kinase 1.	Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily.	0.998
RIPK1	TBK1	ENSANAP00000031154	ENSANAP00000021446	Receptor interacting serine/threonine kinase 1.	TANK binding kinase 1.	0.793
RIPK1	TICAM1	ENSANAP00000031154	ENSANAP00000009967	Receptor interacting serine/threonine kinase 1.	Toll like receptor adaptor molecule 1.	0.978
RIPK1	TLR3	ENSANAP00000031154	ENSANAP00000009875	Receptor interacting serine/threonine kinase 1.	Toll like receptor 3; Belongs to the Toll-like receptor family.	0.965