| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APAF1 | BIRC2 | ENSANAP00000014458 | ENSANAP00000039258 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Baculoviral IAP repeat containing 2. | 0.820 |
| APAF1 | CASP10 | ENSANAP00000014458 | ENSANAP00000002346 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 10; Belongs to the peptidase C14A family. | 0.851 |
| APAF1 | CASP2 | ENSANAP00000014458 | ENSANAP00000009983 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 2; Belongs to the peptidase C14A family. | 0.865 |
| APAF1 | CASP3 | ENSANAP00000014458 | ENSANAP00000014345 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 3; Belongs to the peptidase C14A family. | 0.994 |
| APAF1 | CASP8 | ENSANAP00000014458 | ENSANAP00000022104 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 8; Belongs to the peptidase C14A family. | 0.883 |
| APAF1 | CRADD | ENSANAP00000014458 | ENSANAP00000037360 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | CASP2 and RIPK1 domain containing adaptor with death domain. | 0.442 |
| APAF1 | ENSANAP00000025464 | ENSANAP00000014458 | ENSANAP00000025464 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. | 0.940 |
| APAF1 | PIDD1 | ENSANAP00000014458 | ENSANAP00000020500 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | P53-induced death domain protein 1. | 0.608 |
| BID | CASP10 | ENSANAP00000035623 | ENSANAP00000002346 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Caspase 10; Belongs to the peptidase C14A family. | 0.992 |
| BID | CASP2 | ENSANAP00000035623 | ENSANAP00000009983 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Caspase 2; Belongs to the peptidase C14A family. | 0.978 |
| BID | CASP3 | ENSANAP00000035623 | ENSANAP00000014345 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Caspase 3; Belongs to the peptidase C14A family. | 0.810 |
| BID | CASP8 | ENSANAP00000035623 | ENSANAP00000022104 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Caspase 8; Belongs to the peptidase C14A family. | 0.995 |
| BID | CRADD | ENSANAP00000035623 | ENSANAP00000037360 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | CASP2 and RIPK1 domain containing adaptor with death domain. | 0.448 |
| BID | ENSANAP00000025464 | ENSANAP00000035623 | ENSANAP00000025464 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. | 0.810 |
| BID | PIDD1 | ENSANAP00000035623 | ENSANAP00000020500 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | P53-induced death domain protein 1. | 0.929 |
| BIRC2 | APAF1 | ENSANAP00000039258 | ENSANAP00000014458 | Baculoviral IAP repeat containing 2. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.820 |
| BIRC2 | CASP10 | ENSANAP00000039258 | ENSANAP00000002346 | Baculoviral IAP repeat containing 2. | Caspase 10; Belongs to the peptidase C14A family. | 0.737 |
| BIRC2 | CASP2 | ENSANAP00000039258 | ENSANAP00000009983 | Baculoviral IAP repeat containing 2. | Caspase 2; Belongs to the peptidase C14A family. | 0.826 |
| BIRC2 | CASP3 | ENSANAP00000039258 | ENSANAP00000014345 | Baculoviral IAP repeat containing 2. | Caspase 3; Belongs to the peptidase C14A family. | 0.993 |
| BIRC2 | CASP8 | ENSANAP00000039258 | ENSANAP00000022104 | Baculoviral IAP repeat containing 2. | Caspase 8; Belongs to the peptidase C14A family. | 0.940 |