CSF3 protein (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CSF3

Colony stimulating factor 3. (207 aa)

Predicted Functional Partners:

CSF3R

0.998

PSMC4

0.982

PSMD6

0.982

PSMD13

0.981

PSMC3

0.981

PSMD2

0.979

PSMD11

0.979

PSMD4

0.979

PSMC2

0.979

PSMD7

0.979

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSF3	CSF3R	ENSANAP00000010039	ENSANAP00000027687	Colony stimulating factor 3.	Colony stimulating factor 3 receptor.	0.998
CSF3	PSMC2	ENSANAP00000010039	ENSANAP00000030930	Colony stimulating factor 3.	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	0.979
CSF3	PSMC3	ENSANAP00000010039	ENSANAP00000039378	Colony stimulating factor 3.	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.981
CSF3	PSMC4	ENSANAP00000010039	ENSANAP00000029165	Colony stimulating factor 3.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.982
CSF3	PSMD11	ENSANAP00000010039	ENSANAP00000007452	Colony stimulating factor 3.	Proteasome 26S subunit, non-ATPase 11.	0.979
CSF3	PSMD13	ENSANAP00000010039	ENSANAP00000003944	Colony stimulating factor 3.	Proteasome 26S subunit, non-ATPase 13.	0.981
CSF3	PSMD2	ENSANAP00000010039	ENSANAP00000002394	Colony stimulating factor 3.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.979
CSF3	PSMD4	ENSANAP00000010039	ENSANAP00000011866	Colony stimulating factor 3.	Proteasome 26S subunit, non-ATPase 4.	0.979
CSF3	PSMD6	ENSANAP00000010039	ENSANAP00000036111	Colony stimulating factor 3.	Proteasome 26S subunit, non-ATPase 6.	0.982
CSF3	PSMD7	ENSANAP00000010039	ENSANAP00000033125	Colony stimulating factor 3.	MPN domain-containing protein.	0.979
CSF3R	CSF3	ENSANAP00000027687	ENSANAP00000010039	Colony stimulating factor 3 receptor.	Colony stimulating factor 3.	0.998
PSMC2	CSF3	ENSANAP00000030930	ENSANAP00000010039	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	Colony stimulating factor 3.	0.979
PSMC2	PSMC3	ENSANAP00000030930	ENSANAP00000039378	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.999
PSMC2	PSMC4	ENSANAP00000030930	ENSANAP00000029165	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.999
PSMC2	PSMD11	ENSANAP00000030930	ENSANAP00000007452	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 11.	0.998
PSMC2	PSMD13	ENSANAP00000030930	ENSANAP00000003944	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 13.	0.998
PSMC2	PSMD2	ENSANAP00000030930	ENSANAP00000002394	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.997
PSMC2	PSMD4	ENSANAP00000030930	ENSANAP00000011866	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 4.	0.999
PSMC2	PSMD6	ENSANAP00000030930	ENSANAP00000036111	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 6.	0.999
PSMC2	PSMD7	ENSANAP00000030930	ENSANAP00000033125	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	MPN domain-containing protein.	0.998