Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SLC4A4Anion exchange protein. (1126 aa)    
Predicted Functional Partners:
AHCYL1
Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family.
    
 
 0.906
ENSANAP00000024430
Uncharacterized protein.
    
 
 0.713
AHCYL2
Adenosylhomocysteinase like 2.
    
 
 0.713
GC
GC vitamin D binding protein.
      
 0.683
NPHS2
NPHS2 stomatin family member, podocin.
    
 0.561
NPFFR2
Neuropeptide FF receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.555
EVC
EvC ciliary complex subunit 1.
   
  
 0.514
HECTD4
HECT domain E3 ubiquitin protein ligase 4.
      
 0.512
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]
   
 
 0.481
SLC9A3
Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
    
 
 0.478
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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