Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DUOX2Dual oxidase 2. (1549 aa)    
Predicted Functional Partners:
DUOXA2
Dual oxidase maturation factor 2.
  
 0.999
DUOX1
Dual oxidase 1.
  
 
0.991
DUOXA1
Dual oxidase maturation factor 1.
   
 0.979
NOXO1
NADPH oxidase organizer 1.
    
 0.918
CYBA
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
   
 0.879
NCF1
Neutrophil cytosolic factor 1.
   
 0.870
NCF4
Neutrophil cytosolic factor 4.
   
 0.808
NCF2
Neutrophil cytosolic factor 2.
   
 0.794
NOXA1
NADPH oxidase activator 1.
   
 0.794
NOX4
NADPH oxidase 4.
     
0.676
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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