Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
XPNPEP3X-prolyl aminopeptidase 3. (507 aa)    
Predicted Functional Partners:
METAP1
Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
     
 0.731
C8A
Complement C8 alpha chain.
      
 0.697
AK2
Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
   
   0.687
LOC105733134
Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
   
   0.687
EDNRB
Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.
      
 0.679
C1S
Complement C1s; Belongs to the peptidase S1 family.
    
 
 0.662
DPP8
Dipeptidyl peptidase 8; Belongs to the peptidase S9B family.
      
 0.661
XPNPEP2
X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family.
      
 0.655
CC2D1A
Coiled-coil and C2 domain containing 1A.
    
 
 0.632
ANKS3
Ankyrin repeat and sterile alpha motif domain containing 3.
      
 0.617
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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