STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (781 aa)    
Predicted Functional Partners:
ENSANAP00000011966
WD_REPEATS_REGION domain-containing protein.
   
 
 0.944
FAM53C
Family with sequence similarity 53 member C.
    
 
 0.842
FAM117B
Family with sequence similarity 117 member B.
    
 
 0.831
RNF169
Ring finger protein 169.
    
 
 0.830
RAD54L2
RAD54 like 2.
    
 
 0.776
LIN52
Lin-52 DREAM MuvB core complex component.
    
 0.773
WDR26
WD repeat domain 26.
   
   0.772
MED13L
Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
  
 0.703
C10orf71
Chromosome 10 open reading frame 71.
    
 
 0.700
LIN54
Lin-54 DREAM MuvB core complex component.
   
 0.696
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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