HBEGF protein (Aotus nancymaae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

HBEGF

Heparin binding EGF like growth factor. (208 aa)

Predicted Functional Partners:

ERBB4

0.985

EGFR

0.984

GPC1

0.900

MMP9

0.892

MMP2

0.879

MMP14

0.877

MMP17

0.876

MMP16

0.874

MMP24

0.874

ERBB3

0.873

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGFR	ERBB3	ENSANAP00000037076	ENSANAP00000015882	Epidermal growth factor receptor.	Erb-b2 receptor tyrosine kinase 3.	0.993
EGFR	ERBB4	ENSANAP00000037076	ENSANAP00000032696	Epidermal growth factor receptor.	Receptor protein-tyrosine kinase.	0.966
EGFR	GPC1	ENSANAP00000037076	ENSANAP00000033129	Epidermal growth factor receptor.	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.404
EGFR	HBEGF	ENSANAP00000037076	ENSANAP00000015606	Epidermal growth factor receptor.	Heparin binding EGF like growth factor.	0.984
EGFR	MMP9	ENSANAP00000037076	ENSANAP00000029363	Epidermal growth factor receptor.	Matrix metallopeptidase 9.	0.492
ERBB3	EGFR	ENSANAP00000015882	ENSANAP00000037076	Erb-b2 receptor tyrosine kinase 3.	Epidermal growth factor receptor.	0.993
ERBB3	ERBB4	ENSANAP00000015882	ENSANAP00000032696	Erb-b2 receptor tyrosine kinase 3.	Receptor protein-tyrosine kinase.	0.969
ERBB3	HBEGF	ENSANAP00000015882	ENSANAP00000015606	Erb-b2 receptor tyrosine kinase 3.	Heparin binding EGF like growth factor.	0.873
ERBB4	EGFR	ENSANAP00000032696	ENSANAP00000037076	Receptor protein-tyrosine kinase.	Epidermal growth factor receptor.	0.966
ERBB4	ERBB3	ENSANAP00000032696	ENSANAP00000015882	Receptor protein-tyrosine kinase.	Erb-b2 receptor tyrosine kinase 3.	0.969
ERBB4	HBEGF	ENSANAP00000032696	ENSANAP00000015606	Receptor protein-tyrosine kinase.	Heparin binding EGF like growth factor.	0.985
GPC1	EGFR	ENSANAP00000033129	ENSANAP00000037076	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Epidermal growth factor receptor.	0.404
GPC1	HBEGF	ENSANAP00000033129	ENSANAP00000015606	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Heparin binding EGF like growth factor.	0.900
HBEGF	EGFR	ENSANAP00000015606	ENSANAP00000037076	Heparin binding EGF like growth factor.	Epidermal growth factor receptor.	0.984
HBEGF	ERBB3	ENSANAP00000015606	ENSANAP00000015882	Heparin binding EGF like growth factor.	Erb-b2 receptor tyrosine kinase 3.	0.873
HBEGF	ERBB4	ENSANAP00000015606	ENSANAP00000032696	Heparin binding EGF like growth factor.	Receptor protein-tyrosine kinase.	0.985
HBEGF	GPC1	ENSANAP00000015606	ENSANAP00000033129	Heparin binding EGF like growth factor.	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.900
HBEGF	MMP14	ENSANAP00000015606	ENSANAP00000006501	Heparin binding EGF like growth factor.	Matrix metallopeptidase 14.	0.877
HBEGF	MMP16	ENSANAP00000015606	ENSANAP00000004533	Heparin binding EGF like growth factor.	Matrix metallopeptidase 16.	0.874
HBEGF	MMP17	ENSANAP00000015606	ENSANAP00000027326	Heparin binding EGF like growth factor.	Matrix metallopeptidase 17.	0.876