node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSANAP00000035706 | HGS | ENSANAP00000035706 | ENSANAP00000006705 | Ubiquitin-like domain-containing protein. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.794 |
ENSANAP00000035706 | UEVLD | ENSANAP00000035706 | ENSANAP00000018522 | Ubiquitin-like domain-containing protein. | UEV and lactate/malate dehyrogenase domains. | 0.895 |
ENSANAP00000035706 | VPS28 | ENSANAP00000035706 | ENSANAP00000007521 | Ubiquitin-like domain-containing protein. | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. | 0.572 |
ENSANAP00000035706 | VPS36 | ENSANAP00000035706 | ENSANAP00000010670 | Ubiquitin-like domain-containing protein. | Vacuolar protein sorting 36 homolog. | 0.909 |
ENSANAP00000035706 | ZFYVE1 | ENSANAP00000035706 | ENSANAP00000003013 | Ubiquitin-like domain-containing protein. | Zinc finger FYVE-type containing 1. | 0.705 |
ENSANAP00000035706 | ZFYVE19 | ENSANAP00000035706 | ENSANAP00000037125 | Ubiquitin-like domain-containing protein. | Zinc finger FYVE-type containing 19. | 0.705 |
ENSANAP00000036022 | HGS | ENSANAP00000036022 | ENSANAP00000006705 | Uncharacterized protein. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.794 |
ENSANAP00000036022 | UEVLD | ENSANAP00000036022 | ENSANAP00000018522 | Uncharacterized protein. | UEV and lactate/malate dehyrogenase domains. | 0.895 |
ENSANAP00000036022 | VPS28 | ENSANAP00000036022 | ENSANAP00000007521 | Uncharacterized protein. | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. | 0.572 |
ENSANAP00000036022 | VPS36 | ENSANAP00000036022 | ENSANAP00000010670 | Uncharacterized protein. | Vacuolar protein sorting 36 homolog. | 0.921 |
ENSANAP00000036022 | ZFYVE1 | ENSANAP00000036022 | ENSANAP00000003013 | Uncharacterized protein. | Zinc finger FYVE-type containing 1. | 0.705 |
ENSANAP00000036022 | ZFYVE19 | ENSANAP00000036022 | ENSANAP00000037125 | Uncharacterized protein. | Zinc finger FYVE-type containing 19. | 0.705 |
HGS | ENSANAP00000035706 | ENSANAP00000006705 | ENSANAP00000035706 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Ubiquitin-like domain-containing protein. | 0.794 |
HGS | ENSANAP00000036022 | ENSANAP00000006705 | ENSANAP00000036022 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Uncharacterized protein. | 0.794 |
HGS | MVB12A | ENSANAP00000006705 | ENSANAP00000033783 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Multivesicular body subunit 12A. | 0.757 |
HGS | MVB12B | ENSANAP00000006705 | ENSANAP00000006803 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Multivesicular body subunit 12B. | 0.820 |
HGS | UBA52 | ENSANAP00000006705 | ENSANAP00000039916 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Ubiquitin A-52 residue ribosomal protein fusion product 1. | 0.794 |
HGS | UEVLD | ENSANAP00000006705 | ENSANAP00000018522 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | UEV and lactate/malate dehyrogenase domains. | 0.923 |
HGS | VPS28 | ENSANAP00000006705 | ENSANAP00000007521 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. | 0.900 |
HGS | VPS36 | ENSANAP00000006705 | ENSANAP00000010670 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar protein sorting 36 homolog. | 0.894 |