CASP6 protein (Aotus nancymaae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

CASP6

Caspase 6; Belongs to the peptidase C14A family. (339 aa)

Predicted Functional Partners:

CASP8

0.975

CASP9

0.930

APAF1

0.928

LMNA

0.893

LMNB1

0.883

LMNB2

0.883

APPL1

0.875

APPL2

0.875

CASP10

0.822

CENPI

0.782

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	CASP10	ENSANAP00000014458	ENSANAP00000002346	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 10; Belongs to the peptidase C14A family.	0.930
APAF1	CASP6	ENSANAP00000014458	ENSANAP00000019710	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 6; Belongs to the peptidase C14A family.	0.928
APAF1	CASP8	ENSANAP00000014458	ENSANAP00000022104	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 8; Belongs to the peptidase C14A family.	0.947
APAF1	CASP9	ENSANAP00000014458	ENSANAP00000034772	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 9; Belongs to the peptidase C14A family.	0.999
APPL1	APPL2	ENSANAP00000013255	ENSANAP00000034448	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.988
APPL1	CASP10	ENSANAP00000013255	ENSANAP00000002346	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Caspase 10; Belongs to the peptidase C14A family.	0.875
APPL1	CASP6	ENSANAP00000013255	ENSANAP00000019710	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Caspase 6; Belongs to the peptidase C14A family.	0.875
APPL1	CASP8	ENSANAP00000013255	ENSANAP00000022104	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Caspase 8; Belongs to the peptidase C14A family.	0.875
APPL1	CASP9	ENSANAP00000013255	ENSANAP00000034772	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Caspase 9; Belongs to the peptidase C14A family.	0.875
APPL2	APPL1	ENSANAP00000034448	ENSANAP00000013255	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	0.988
APPL2	CASP10	ENSANAP00000034448	ENSANAP00000002346	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Caspase 10; Belongs to the peptidase C14A family.	0.875
APPL2	CASP6	ENSANAP00000034448	ENSANAP00000019710	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Caspase 6; Belongs to the peptidase C14A family.	0.875
APPL2	CASP8	ENSANAP00000034448	ENSANAP00000022104	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Caspase 8; Belongs to the peptidase C14A family.	0.875
APPL2	CASP9	ENSANAP00000034448	ENSANAP00000034772	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Caspase 9; Belongs to the peptidase C14A family.	0.875
CASP10	APAF1	ENSANAP00000002346	ENSANAP00000014458	Caspase 10; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.930
CASP10	APPL1	ENSANAP00000002346	ENSANAP00000013255	Caspase 10; Belongs to the peptidase C14A family.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	0.875
CASP10	APPL2	ENSANAP00000002346	ENSANAP00000034448	Caspase 10; Belongs to the peptidase C14A family.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.875
CASP10	CASP6	ENSANAP00000002346	ENSANAP00000019710	Caspase 10; Belongs to the peptidase C14A family.	Caspase 6; Belongs to the peptidase C14A family.	0.822
CASP10	CASP8	ENSANAP00000002346	ENSANAP00000022104	Caspase 10; Belongs to the peptidase C14A family.	Caspase 8; Belongs to the peptidase C14A family.	0.992
CASP10	CASP9	ENSANAP00000002346	ENSANAP00000034772	Caspase 10; Belongs to the peptidase C14A family.	Caspase 9; Belongs to the peptidase C14A family.	0.639