STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA2Pleckstrin homology domain containing A2. (425 aa)    
Predicted Functional Partners:
MYSM1
Myb like, SWIRM and MPN domains 1.
    
 0.986
PTPN13
Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.
    
 0.859
KDM6B
Lysine demethylase 6B.
    
 0.802
KDM6A
Lysine demethylase 6A.
    
 0.802
GLYR1
Glyoxylate reductase 1 homolog.
    
   0.722
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 
 0.694
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 
 0.677
POLR2B
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.654
POLR2C
RNA polymerase II subunit C.
    
 0.647
SETD2
SET domain containing 2, histone lysine methyltransferase.
    
 0.644
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.